June 27, 2026 · ISCA 2026 · Raleigh, NC

Architecture 2.0

Workshop on Agentic AI for Computing Systems Design

About the Workshop

The Architecture 2.0 workshop brings together researchers and practitioners exploring the intersection of agentic artificial intelligence and computer systems. As autonomous agents and AI workflows continue to transform how we design, optimize, and evaluate computing systems, this workshop provides a venue for presenting cutting-edge research and fostering collaboration on agent-based methodologies across the hardware stack.

The workshop focuses on Agentic AI for Systems Design, spanning computer architecture, programming languages, and operating systems. We aim to bring together researchers and practitioners applying agentic tools and autonomous AI techniques to systems challenges, providing a platform for work-in-progress and completed research that advances the state of the art or opens new directions for agent-driven systems engineering.

The workshop centers on a Call for Papers for research submissions, bringing together work that applies agentic AI across architecture and systems design.

📅

Date

Saturday, June 27, 2026

📍

Location

ISCA 2026 · Raleigh, NC
Room 306B

Workshop Schedule

8:00–8:15 Welcome and Opening Remarks
8:15–9:15 Session 1: Agentic EDA — From RTL Optimization to Design-Space Exploration
  • MAESTRO: A Multi-Agent EDA Orchestrator for Autonomous FPGA Design Closure 8:15–8:30 · Saher Elsayed
  • Intelligent Equality Saturation: From Hierarchical Prospection to a Minimal Implementation 8:30–8:45 · Youwei Xiao, Chenyun Yin, Yun Liang
  • AgenticDSE: A Multi-Agent Design Space Exploration Framework with Multi-Phase Bayesian Optimization for Chiplet Accelerators 8:45–9:00 · Zhantong Zhu, Zhuolin Li, Kangbo Bai, Hongou Li, Tianyu Jia
  • Dr. RTL: Autonomous Agentic RTL Optimization through Tool-Grounded Self-Improvement 9:00–9:15 · Wenji Fang, Zhiyao Xie
9:15–10:00 Session 2: Agentic Systems for Runtime Profiling, Serving, and Diagnosis
  • Towards Agentic Offline Profiling for Speculative Load Micro-Op Fusion 9:15–9:30 · Deepanjali Mishra, Tanvir Ahmed Khan, Gilles Pokam, Heiner Litz, Akshitha Sriraman
  • Argus: Agentic, Reference-Calibrated, Tree-Guided, System-Level Bottleneck Localization 9:30–9:45 · Vlad-Petru Nitu, Harsh Songara, Konstantinos Sgouras, Spiros Galanopoulos, Konstantinos Kanellopoulos, Onur Mutlu
  • Dyserve: Dynamic Strategy Generation for Agent Serving 9:45–10:00 · Jiayi Qian, Zishen Wan, Hanchen Yang, Souvik Kundu, Tushar Krishna
10:00–10:30
Coffee Break (with Poster Session)
10:30–11:15 Plenary Talk: Saman Amarasinghe (MIT)
  • Compiler 2.0: Languages and Compilers in the Era of Machine Learning

    Abstract: The genius of FORTRAN, introduced in 1957, was not just that it was the first high-level language, but that it made hardware disappear. The same FORTRAN program could run on an IBM System/360, a DEC PDP-8, a CDC 6600, or even a Cray-1 with enough performance that most programmers never had to touch assembly or write architecture-specific code.

    Over time, as hardware and software grew more complex, compilers quietly lost the ability to maintain this abstraction. Multicores, complex vector instructions, and specialized accelerators have all pushed more of the performance burden back onto the programmer. Today we have, in many ways, come a full circle. For example, getting peak performance from NVIDIA's V100, A100, H100, and B100 families often requires different, architecture-specific CUDA kernels and, on the latest parts, even hand-written PTX assembly to fully exploit tensor cores and the Tensor Memory Accelerator. To the best of our knowledge, the Apple/Arm SME accelerator does not even have a high-level compiler, and most high-performance code must be written using intrinsics or assembly.

    This raises a fundamental question: can the next generation of compilers restore the original promise of the high-level programming languages—hiding architectural complexity while still delivering near-peak performance?

    In this talk, I will argue that the answer is yes, and I will outline a path forward for us to modernize compilers—both to make them far more effective on today's architectures and to radically simplify how we build them—by creating proper abstractions and leveraging machine learning and other modern techniques.

    Bio: Saman Amarasinghe is the Thomas and Gerd Perkins Professor in the Department of Electrical Engineering and Computer Science at MIT and leads the Commit compiler research group in MIT's Computer Science & Artificial Intelligence Laboratory (CSAIL). Born in Sri Lanka and schooled at Royal College, Colombo, he is a graduate of Cornell University and earned his Master's and PhD degrees from Stanford University. He was elected as an ACM Fellow in 2019.

11:15–12:00 Plenary Talk: Sagar Karandikar (UC Berkeley)
  • CHIA: An open-source framework for principled, agentic AI-driven hardware/software co-design research

    Abstract: In the coming years, agentic AI is poised to take HW/SW co-design to the next level. This talk will cover several aspects of my group's work on AI-driven co-design, including successes in automated architectural discovery and our hot-off-the-presses open-source framework for AI-driven hardware/software co-design called CHIA (https://chialoops.ai).

    We will begin by discussing ArchAgent (OpenReview, Nov. 2025), the first agentic, evolutionary, generative AI system that can automatically design new hardware mechanisms (i.e., not just parameter tuning). ArchAgent achieves SoTA solutions to established problems (e.g., cache replacement competitions on SPEC) without human intervention. In addition to a technical deep dive, we will cover the key challenges/lessons learned and the broad implications of systems like ArchAgent on the field of computer architecture.

    On the way to addressing these challenges, we will review the past decade of advances in agile hardware/software co-design that have been driven by the application of software engineering principles to hardware design. These include concepts like building flexible hardware generators (Chipyard RISC-V SoC Framework), cost-efficient cloud scaling and automatic design transformation (FireSim FPGA-accelerated HW Simulator), and process/tool portability and modularity (Hammer ASIC Flow).

    Given our learnings from both of these domains, we will introduce the brand new (released yesterday!) CHIA project (https://chialoops.ai, OpenReview, June 2026). CHIA is an open-source hardware/software co-design framework for agile and principled research on the application of AI to co-design. CHIA treats the productive construction and scalable deployment of the co-design flow itself as a first-class objective. In CHIA, agentic AI-driven hardware and software design flows are expressed as CHIA loops: directed cyclic graphs whose nodes execute various system-on-chip design tools, microarchitectural simulators, software build systems, AI models, evolutionary coding agents, and more. The CHIA library provides node implementations for many popular tools, including Chipyard, gem5, ChampSim, FireSim, Hammer (thus several commercial ASIC CAD tools), Vivado, AlphaEvolve, AdaEvolve, and many others. We will discuss several case studies to show CHIA's capabilities and are excited to see what the community does with CHIA!

    Bio: Sagar Karandikar is an Assistant Professor of Electrical Engineering and Computer Sciences (EECS) at UC Berkeley and the Jean and Hing Wong Foundation Faculty Fellow at UC Berkeley. His group works on areas including agile, open-source, AI/ML-infused hardware/software co-design methodologies, hardware accelerator and server system-on-chip design, and full-stack (HW + SW) system optimization and profiling. His work has received several recognitions, including an ISCA@50 25-year Retrospective selection, an IEEE Micro Top Picks selection, an IEEE Micro Top Picks honorable mention, a MICRO Distinguished Artifact Award, an ISCA Distinguished Artifact Award, and more. His work, including the open Chipyard and FireSim projects, is also widely used in the community. For example, FireSim has been used (not only cited) in over 85 peer-reviewed publications from first authors at over 35 institutions, in the development of commercially available chips, and as a standard host platform for DARPA/IARPA programs. Other recognitions he has received include: the 2025 ACM SIGARCH/IEEE CS TCCA Outstanding Dissertation Award, a Google ML and Systems Junior Faculty Award, the David J. Sakrison Memorial Prize, and selection as a DARPA Riser. More info: https://sagark.org

12:00–13:30
Lunch Break
13:30–14:15 Plenary Talk: Dimitrios Skarlatos (CMU)
  • Architecture & Systems in the Era of Agentic Co-Design

    Abstract: The AI datacenter stack runs on hardware-software contracts written for a world where humans wrote all the code and designed all the hardware, but both are now changing. With datacenters projected to draw over 1,000 TWh annually and the next efficiency leap demanding two orders of magnitude of improvement, renegotiating the hardware-software contract is no longer optional.

    This talk turns head-on to agentic co-design: from embedding learning inside low-level mechanisms with works like LVM, to systems like LithOS that rethink the OS contract over GPUs for AI and agentic serving, to full agentic co-design with our progress on Agentic Architect, a framework for LLM-driven architecture design space exploration and optimization.

    Architects are uniquely positioned to close the agentic loop. The benchmarks, simulators, and metrics are already here. In the last part of the talk I'll cover a few of the things that are still missing. This is a call to action for the community best positioned to define the next generation of the system stack: our community.

    Bio: Dimitrios Skarlatos is an assistant professor in the Computer Science Department at Carnegie Mellon University. His research bridges computer architecture and operating systems with a focus on AI datacenter efficiency, privacy, and scalability. His work has been deployed in production datacenters and upstreamed into the Linux kernel. He has received the IEEE CS TCCA Young Computer Architect Award, the NSF CAREER Award, the Intel Rising Star Award and the Intel Outstanding Researcher award, a Linux Foundation Faculty Award, an ISCA Best Paper Award, two ASPLOS Best Paper Awards, a CACM Research Highlight, four IEEE MICRO Top Picks, the joint ACM SIGARCH & IEEE CS TCCA Outstanding Dissertation Award, and over a dozen industry faculty awards from Amazon, AMD, Intel, Meta, Oracle, and VMware. His recent work led to the founding of LithosAI.

14:15–15:00 Session 3: Benchmarking and Evaluation of Agentic Architecture
  • Benchmarking Agentic HLS Design Tasks With HLS-Eval 14:15–14:30 · Stefan Abi-Karam, Callie Hao
  • Fail2Bench: Turning RTL Agent Failures into a Self-Curating Benchmark 14:30–14:45 · Aryan Chhabra, Sumedh Narahari, Shritan Settipalli, Aadarsh Sivaraman
  • Punctuated Stagnation 14:45–15:00 · Mahesh Madhav
15:00–15:30 Tutorial — ArchEval: Measuring AI Agents as Computer Architects
  • Chenyu Wang, Zishen Wan, Jeffrey Ma, Shvetank Prakash, Zhenting Qi, Haebin Do, Andy Cheng, Arya Tschand, Jiahe Shi, Yilun Du, Vijay Janapa Reddi
15:30–16:00
Coffee Break (with Poster Session)
16:00–16:45 Plenary Talk: Qijing Jenny Huang (NVIDIA)
  • Design Space Exploration in the Age of AI Architects

    Abstract: Design space exploration (DSE) is central to computer architecture, helping designers navigate large spaces of algorithmic, architectural, and mapping choices to optimize performance, power, and area. Yet current DSE flows still require substantial manual effort and remain largely bounded by human-defined abstractions, performance models, and search spaces.

    As the field approaches its "AlphaZero moment", this talk looks beyond using AI to accelerate search within a fixed design space. The larger opportunity is to build AI architects: agentic systems that automate under-formalized design tasks, perform knowledge-guided search, and expand exploration beyond choices explicitly specified by humans.

    To ground this vision, we revisit existing DSE workflows to identify where manual effort remains and where generative AI can meaningfully extend automation. As one example, we present SOLAR, an agentic framework that interprets algorithms and translates them into performance-model-ready representations, showing how AI architects can support the less structured stages of DSE.

    Finally, we connect AI for architecture to the broader AI-for-X landscape, especially AI for coding. We discuss transferable lessons from coding agents while highlighting challenges unique to hardware architecture. We conclude with a call for new benchmarks, methodologies, and infrastructure to build creative yet trustworthy AI architects for scalable DSE and to accelerate hardware innovation.

    Bio: Qijing Jenny Huang is a Senior Research Scientist at NVIDIA. Her research focuses on AI for computer architecture exploration, with the goal of advancing full-stack automation of architecture design. A central theme of her work is deriving speed-of-light performance limits for emerging workloads and technologies, and developing automatic methods to close the gap between those limits and practical systems. Her broader research spans algorithm-hardware co-design for deep learning, agile design methodologies, and scheduling optimization. Her work has been recognized by IEEE Micro Top Picks, an ISCA Best Paper nomination, and EECS Rising Stars. She received her Ph.D. in Computer Science from UC Berkeley.

16:45–17:30 Session 4: Agentic Optimization for Kernels, Compilers, and Hardware Knowledge
  • HDLxGraph: Bridging Large Language Models and HDL Repositories via HDL Graph Databases 16:45–17:00 · Jiayin Qin, Pingqing Zheng, Fuqi Zhang, Zishen Wan, Shang Wu, Yu Cao, Caiwen Ding, Yang Katie Zhao
  • From Skills to Tracelets: Dependency-Guided Transfer for LLM Kernel Agents 17:00–17:15 · Shuoming Zhang, Ruiyuan Xu, Qiuchu Yu, Guangli Li, Huimin Cui, Jiacheng Zhao
  • AccelOpt: A Self-Improving LLM Agentic System for AI Accelerator Kernel Optimization 17:15–17:30 · Genghan Zhang, Shaowei Zhu, Anjiang Wei, Zhenyu Song, Allen Nie, Zhen Jia, Nandita Vijaykumar, Yida Wang, Kunle Olukotun
17:30–18:00
Poster Session

Call for Papers: Agentic AI for Architecture & Systems Design

We invite submissions that explore the use of agentic frameworks, autonomous workflows, and artificial intelligence to design, analyze, optimize, or evaluate computer systems. The workshop aims to bring together researchers and practitioners applying agent-based AI techniques to systems challenges across the hardware stack.

We welcome both work-in-progress and completed research that advances the state of the art or opens new directions for agent-driven hardware methodologies and systems research.

Note: The event will not have formal proceedings, and authors are free to publish extended versions of their work in other conferences and journals.

Submission Type

We welcome works of three different formats:

  • Early/Work-in-Progress Research
  • Extended Abstract of Completed Research
  • Position/Opinion Papers

Topics of Interest

Submissions should focus on AI for Systems, spanning computer architecture, programming languages, and operating systems, including but not limited to the following areas:

Computer Architecture

  • Agent-driven microarchitecture design, tuning, and exploration
  • Agent-driven chip design, hardware code generation, synthesis, and place-and-route
  • Agent-driven design space exploration and architectural trade-off analysis
  • Agent-optimized processor, accelerator, and heterogeneous system design
  • GPU, TPU, and accelerator architectures and kernel optimization via autonomous agents
  • Memory systems, cache hierarchies, interconnects, and storage optimization using agentic AI
  • Agent-based performance, power, energy, and reliability modeling
  • Agentic workflows and surrogate models to accelerate architectural simulation and evaluation
  • Autonomous methods for identifying architectural bottlenecks and inefficiencies

Systems

  • Agent-assisted compilers, program analysis, and code generation
  • Automatic kernel transformation, scheduling, and tuning
  • Cross-layer co-design across compilers, runtimes, operating systems, and hardware via agentic workflows
  • Agent-driven scheduling, resource management, and system-level optimization
  • Intelligent and autonomous runtime systems for heterogeneous and accelerator-rich platforms
  • Agent-driven memory management, caching, and I/O policies

Infrastructure and Evaluation

  • Datasets tailored for agentic hardware and systems evaluation
  • Benchmarks for assessing agent-driven system workflows
  • Open-source infrastructure enabling agent-driven approaches across the architecture–language–OS stack

Reviewing Details

Submission and Platform: All submissions will be handled through the OpenReview platform. The review process will be single-blind; therefore, submissions should include author names and affiliations and should not be anonymized.

Decisions: All accept/reject decisions will be made exclusively by the organizing committee. Submissions will be evaluated for relevance to the event's theme, technical novelty, and clarity of presentation.

Submission Details

Submission deadline: May 19, 2026 (AoE) (Deadline Extended)
Author Notification: May 22, 2026
Paper length: (This is not a strict limit, authors are encouraged to adhere to it if possible.)
  • Early/Work-in-Progress Research: 4 pages
  • Extended Abstract of Completed Research: 2 pages (with pointer to full-length paper)
  • Position/Opinion Papers: 2 pages

Resources

Organizing Team

Zishen Wan

Zishen Wan

Harvard University

Chenyu Wang

Chenyu Wang

Harvard University

Andy Cheng

Andy Cheng

Harvard University

Shvetank Prakash

Shvetank Prakash

Harvard University

Arya Tschand

Arya Tschand

Harvard University

Zander Ingare

Zander Ingare

Harvard University

Ankita Nayak

Ankita Nayak

Gimlet Labs

Vijay Janapa Reddi

Vijay Janapa Reddi

Harvard University